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Your Family's Health
What Are All Those Tests... And Why Do I Need Them?
by Randy A. Birken, M.D.
Just about from the instant you were born, there has been a schedule -- or at the very least guidelines -- to outline when you need to take care of certain aspects of your heath.  First, there were all those immunizations for diseases almost no one around these days has ever heard of (thank goodness) -- diphtheria, typhoid, whooping cough, polio.  Then, like clockwork, every few years or so, Mom  would drag you back to the doctor’s office for a whole new round of shots.  They tried to convince you that all of this was “for your own good,” but you weren’t buying it.  You did get the message, however, that trips to the doctor’s office often involved pain and having to take your clothes off. 

By the time you reached the important teen years, and successfully negotiated the rites of becoming a “woman,” the doctor’s visit routine had been confirmed numerous times.  There were more surprises waiting for you, however, when Mom decided it was time you had your first appointment with a gynecologist.  If you were lucky, the doctor was born in this century, had a good understanding that his or her patients would rather be anywhere else, and who intuitively knew that whether the patient was a teenager or a senior citizen, women dislike carrying on a conversation when they are the only one undressed. 

Back 40 or 50 years ago, a woman made her first gynecological visit during her 20’s or in preparation for her wedding.  Today, however, the American College of Obstetricians and Gynecologists recommends that young women make their first visit to a gynecologist by age 18 or earlier if she becomes sexually active. 

This initial visit provides a good opportunity to discuss changes that are occurring to her body, and for her to learn about preventive measures -- such as breast self-exams and diagnostic tests that should become part of her health routine for life.  Probably the first of these that will be performed is the Pap Test. 

The Pap Test

The Pap Test -- which, incidentally, has been around for sixty years, thanks to a Dr. George Papanicolaou -- is credited with saving the lives of hundreds of thousands of women, and as being the best early warning system for cervical cancer available.  In the 1950’s, for example, about 20,000 women died each year from cervical cancer.  Today, the annual mortality rate for this disease is less than 5,000 -- a number that could be even further reduced if more women would schedule the exam. 

There has been significant progress over the past decade in our understanding of cervical cancer.  We know that cancers arising in the lining of the cervix seem to be related to sexual behavior and exposure because women who have been celibate rarely get this disease.  Those who become sexually active at a young age, however, and who have had multiple sex partners are at a significantly higher risk of getting this cancer.  Research has also shown that certain viruses (of the herpes and papilloma group) play a role in causing about 95 percent of the cases of this disease. 

Scientific studies indicate that some combination of genetic susceptibility, sexual exposure, and contact with some viruses may all be involved.  Fortunately, this is a cancer that can be detected in its earliest, pre-cancerous stage and be cured.  However, once symptoms occur -- vaginal bleeding and discharge between periods and pain during intercourse -- the cervical cancer is often advanced.  This is why having regular Pap Tests is so important. 

The test is relatively simple, quick and painless, and is accomplished in the doctor’s office.  During a pelvic exam, the doctor gently removes cells from the cervix (the narrow neck-like opening of the uterus) with a cotton swab or similar instrument, and places them on a glass slide for a microscopic analysis in a laboratory, where a specially trained technician (cytotechnologist) examines the sample for abnormal cells.  Traditionally, this test has been performed manually, and has been compared to looking for the proverbial needle in a haystack.  Each sample may contain as many as 300,000 cells that have to be examined under a microscope, from which as few as a dozen might be pre-cancerous.  Even so, the test has been incredibly reliable through the years. 

In the past decade, however, advanced computer technology has been introduced that is designed to detect and display abnormal cells on a video monitor for closer inspection.  While this method does appear to provide a closer, second look at abnormal cells, it is not foolproof, either.  None of the tests have a 100 percent accuracy record but, even with false-negative and false-positive readings, this is still an important test that accurately detects significant abnormalities about 90 to 95 percent of  the time. 

Back to the lifelong schedule again...women should schedule Pap Tests according to their doctor’s recommendation.  After three consecutive, normal, annual Pap Tests less frequent testing may be considered, but not less often than every three years...for life.  Remember, the risk for invasive cervical cancer increases with age; the disease is most likely to occur between the ages of 30 and 55.  For those who are at higher risk for cervical cancer  -- early sexual activity, multiple sex partners, a history of sexually transmitted diseases, a history of abnormal Pap Tests, genital warts, or women who smoke -- more frequent Pap Testing is appropriate. 

Sexually Transmitted Diseases

There is growing concern about the prevalence of pelvic inflammatory disease (PID) and sexually transmitted diseases (STD) among the country’s teen population.  Granted, it is hard to get teenagers to think in any tense but the present; however, these infections can alter the course of their adult lives dramatically. 

PID is basically an infection in the pelvic region and upper genital tract caused by an of a group of infectious agents or microorganisms.  Each year, about a million women in this country are diagnosed with this condition.  In many cases, PID is caused by untreated sexually transmitted diseases, making young women and those who have multiple sex partners the most vulnerable. 

Sexually transmitted diseases initially cause infection in the cervix and vagina and, when not promptly treated, the microorganisms can spread to infect the uterus and fallopian tubes, as well.  Gonorrhea and chlamydia are often the culprits, but in many cases, there is more than one organism to blame. 

Chlamydia is transmitted sexually, and may cause symptoms such as painful urination and lower abdominal pain, or it may cause no symptoms at all.  Screening for this condition is simply accomplished from a urine test and it is treated with antibiotics.  The problem is that far too many young women overlook the symptoms and don’t get medical attention, so they run the risk of a more serious infection developing.  There has been such a high incidence of chlamydia that many physicians recommend screening for sexually active young women every six months.  The Centers for Disease Control and Prevention recommends annual screenings. 

Gonorrhea is a highly contagious STD and is, in fact, one of the top 10 reported diseases in this country (about a half million cases), with hundreds of thousands more cases undetected.  Gonorrhea is caused by a bacteria, transmitted through unprotected sex, and is most common in people between the ages of 15 to 29.  This disease causes a few mild symptoms, and can easily go undetected.  The infection usually affects the cervix and reproductive organs, and well as the urethra, and may cause frequent, urgent and painful urination.  The bacteria that causes gonorrhea can spread throughout the body and cause joint pain and stiffness -- and other “remote” symptoms that the sufferer may not immediately relate to an STD.  Once diagnosed, antibiotic therapy can begin, however, it is critical to abstain from sexual activity until the infection is eliminated, and for the sexual partner to be treated, too. 

The symptoms of PID include lower abdominal pain (sometimes severe), a heavy discharge, irregular bleeding, fever and general malaise.  There is no single test for PID, so a number of factors in addition to a physical exam are taken into account in making the diagnosis.  One of the most important of these is to consider the patient’s sexual history and risk factors.  There are many other conditions which can produce the same symptoms, so the doctor must rule out appendicitis, ectopic pregnancy, an ovarian cyst or any other condition which might require immediate surgery or prompt treatment.  When these other serious disorders cannot be ruled out, a laparoscopy may be recommended to allow a visual inspection of the upper genital area.  This is a minimally invasive, outpatient procedure that involves inserting a fiberoptic scope into the abdomen through tiny incisions. 

Many cases of PID go undiagnosed and untreated because the symptoms are never particularly serious and are easily ignored.  Consequently, it is one of the leading causes of infertility for women in their childbearing years.  Most cases can be treated with a broad spectrum antibiotic and a follow up visit.  For the best results, however, the patient’s partner should be treated with antibiotics, as well. 

Breast Care

During a woman’s first gynecological visit -- or perhaps earlier with her family physician -- she will have her first clinical breast exam where her doctor will examine her breasts and armpits, feel for lumps and swollen lymph nodes, and get a general overview of breast “geography.”  This is an ideal time for the doctor, physician’s assistant or nurse to teach the young woman how to perform a breast self exam (BSE) which should become a regular routine for the rest of her life.  Breast cancer does occur in young women in their 20’s and the sooner the habit of BSE is established the more likely she will discover any suspicious lump in the earliest stage when there is the best chance for a cure. 

While there is an ongoing discussion about when women should begin annual mammograms, the general consensus is certainly at or before age 40, and we recommend a baseline mammogram at age 35.  (See All Breasts Are Lumpy...)  We welcome the opportunity to discuss this important topic with our patients and, perhaps more importantly, we understand how anxious you might be waiting for results of your mammogram. so we minimize this wait as much as possible. 

Women and Heart Disease...

Today, most people realize that heart disease can affect both men and women.  What they may not realize is that coronary heart disease is the number one killer of American women. Of the over half million cardiovascular disease fatalities that occur each year, almost half are women.  Unfortunately, studies show that women are less likely to survive heart attacks than men; and at older ages, women who have heart attacks are twice as likely as men are to die from them within a few weeks. 

Ideally, by age 35 women should have regular blood pressure and cholesterol level checks.  If either parent had a history of heart disease, your physician may also recommend a base-line electrocardiogram or stress test.  Then, based on the results of these tests, preventive measures may be recommended -- including modifications in diet and lifestyle, stress management, and certainly smoking cessation -- to minimize risk factors for cardiovascular disease. 

After menopause, women’s risk of heart attack and stroke continues to rise with age. Researchers generally agree that loss of estrogen is a significant contributor to women developing heart disease after menopause, so as that time approaches, hormone replacement therapy is something you will want to discuss with your gynecologist. (See Women’s Heart Health Test)

Avoiding Osteoporosis

Approximately 22 million people in the United States have or are at risk of developing osteoporosis, a bone-thinning condition in which bones slowly lose mass and deteriorate.  The disease,  which mostly affects older women,  is credited with causing about a million fractures each year and can cause chronic and acute pain, and a stooped posture. 

Osteoporosis is not, as previously thought, an inevitable consequence of aging.  Some people are at higher risk for developing the condition and there are new options to prevent and treat the disease -- even if its early signs and symptoms have been detected.  The risk factors include: gender (women are twice as likely to get osteoporosis as men); age (risk increases with age); an immediate family member with the disease; race (Caucasians are at greatest risk); early menopause; extended use of steroid medications (for treating asthma, arthritis, etc.); and cigarette smoking. 

A baseline bone densitometry scan should be done at menopause, with additional scans done at the recommendation of your physician.  This is a painless, non-invasive scan of the lower back or hip that takes only a few minutes to complete.  If the disease is detected in its early stages, exercise, calcium supplements, estrogen replacement therapy and/or medications may be recommended. 

Ovarian Cancer

Ever since Gilda Radner of Saturday Night Live fame died of ovarian cancer a decade ago, women have been even more worried about this potentially deadly disease.  Since then, considerable progress has been made in the diagnosis and treatment of this cancer.  We now know, for example, that about 7 percent of ovarian cancers are linked to a genetic predisposition for both breast and ovarian cancer.  While it now has a 90 percent five-year survival rate when detected early, ovarian cancer can still be lethal if undetected and left untreated.  The problem is that ovarian cancer is difficult to diagnose before the tumor has spread beyond the ovaries. 

Each year, about 25,000 women are diagnosed with ovarian cancer and more than 14,000 die of it.  Most of the cases are in women over age 50, but it occurs in younger women, too.  There are few early symptoms; however, as the tumor grows it puts pressure on organs in the lower abdominal cavity, which can cause changes in bowel or bladder habits, abdominal swelling, indigestion, gas, bloating, pain, as well as weight gain or loss.  The enlarged ovaries may be detected during a pelvic exam and there are now genetic blood tests that can be helpful, but a laparotomy is necessary to reach a definitive diagnosis.  If cancer is confirmed during the laparotomy, surgery to remove the ovary or ovaries may be recommended. 

Unfortunately, there are also other equal opportunity cancers that increasingly affect women:  lung cancer and colon cancer are on the rise in this country.  As the years pass, discuss which tests and screening measures are important and be alert for changes in the way your body functions and feels.  Sometimes, the first signs of what could potentially be serious illness start with a minor symptom that’s easy to ignore.  Don’t.  If something doesn’t feel just right, make an appointment for a check up or call your physician to share your concerns.  Remember, the best chance to cure or successfully treat even a potentially serious illness is right at the outset, so don’t procrastinate...make the call. 

Randy A. Birken, M.D., P.A.
Gynecology/Urogynecology

17070 Red Oak Drive, Suite 201-A
Houston, Texas 77090
(281) 893-1246

drbirken@yourfamilyshealth.com

Dr. Birken graduated Cum Laude from Adelphi University, Garden City, New York and earned his M.D. from the Boston University School of Medicine. He completed his internship and Residency in Obstetrics and Gynecology at Baylor College of Medicine, Houston, Texas, and was then Chief Resident in OB/Gyn at that institution. He completed a Preceptorship in Urogynecology at the University of California, Irvine. Dr. Birken is a Diplomate of the American Board of Obstetricians and Gynecologists, and was recertified in June 1995. He is the father of three sons, and has served as a Little League baseball coach and as team physician for a youth football league.

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